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Huimin Zhao


Huimin Zhao

Professor, Part-time Principal Investigator


Ph. D., Chemical Engineering, 1998, California Institute of Technology

B. S., Biology, 1992, University of Science and Technology of China


Specializations: Synthetic Biology, Metabolic Engineering, Industrial Biotechnology


Research focuses:

  • Design and engineering of microbial cell factories for synthesis of fuels and chemicals
    Enzyme catalysis
    Natural product biosynthesis
    Gene regulation

Selected Recent Publications: (within 2 years)

  • S. Shi, Y. Liang, M. Zhang,  E. Ang, and H. Zhao. “A Highly Efficient Single-step, Markerless, and Multi-copy Strategy for Chromosomal Integration of Full Biochemical Pathways in Saccharomyces cerevisiae.” Metabolic Engineering, 33, 19-27 (2016).
    S. Shi, T. Si, Z. Liu, H. Zhang, E. Ang, and H. Zhao. “Metabolic Engineering of an Endogenous Pathway for n-Butanol Production in Saccharomyces cerevisiae.” Scientific Reports6:25675 (2016).
    M. M. Zhang, F. Wong, Y. Wang, S. Luo, Y. H. Lim, E. Heng, W. L. Yeo, R. E Cobb, B. Enghiad, E. Ang, and H. Zhao. “CRISPR-Cas9 Strategy for Activation of Silent Streptomyces Biosynthetic Gene Clusters.” Nature Chemical Biology, 13, 607-609 (2017).
    R. Chao, S. Miresh, T. Si, and H. Zhao. “Engineering Biological Systems using Automated Biofoundries.” Metabolic Engineering, 42, 98-108 (2017).
    J. Liang, Z. Liu, E. Ang, and H. Zhao. “Twin-primer Non-enzymatic DNA Assembly: an Efficient and Accurate Multi-part DNA Assembly Method.” Nucleic Acids Research, 45: e94 (2017).
    T. Si, R. Chao, Y. Min, Y. Wu, W. Ren, and H. Zhao. “Automated Multiplex Genome-scale Engineering in Yeast.” Nature Communications, 8:15187 (2017).
    S. Shi, Y. W. Choi, and H. Zhao, M. H. Tan, E. L. Ang. “Discovery and engineering of a 1-Butanol Biosensor in Saccharomyces cerevisiae.” Bioresource TechnologyDOI: 10.1016/j.biortech.2017.06.114.






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