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Jin-ping Li

 

Jin-ping Li

Professor, Part-time Principal Investigator

Education:

PhD. Dept. of Biochemistry, Uppsala University, Sweden, 1990

MSc. Institute of Radiation Medicine, Beijing, China, 1983

M.D. Shanxi Medical University, Taiyuan, China, 1977

SpecializationsMedicinal biochemistry and glycobiology

 

Research focuses:

 

 

 

 

 

 

 

 

 

 

Functional biology of carbohydrate polymers
Preparation of oligosaccharides for treatment of diseases

 

 

Recent Publications:

 

 

 

 

 

 

 

 

 

 

 

 

Digre A, Singh K, Åbrink M, Reijmers RM, Sandler S, Vlodavsky I, and Li J-P*  (2017) Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis Sci Rep 7:46229
Fang J, Song T, Lindahl U and Li J-P* (2016) Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis Sci Rep 6:31242
Oskarsson ME, Singh K, Wang J, Vlodavsky I, Li J-P* and Westermark GT (2015) Heparan sulfate proteoglycans are important for islet amyloid formation and islet amyloid polypeptide-induced apoptosis Biol Chem 290(24),15121-15132
Christianson HC, Svensson KJ, van Kuppevelt TH, Li, J-P and Belting M (2013) Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity PNAS 110(43): 17380-17385
Noborn F, O' Callaghan P, Hermansson E, Zhang X, Ancsin J, Damas A, Dacklin I, Presto J, Johansson J, Saraiva M, Lundgren E, Kisilevsky B, Westermark P and Li J-P* (2011) Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein PNAS 108(14), 5584-5589
Feyerabend T, Li J-P*Lindahl U and Rodewald HR (2006) Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells Nat Chem Biol 2(4):195-6.
Escobar Galvis M, Jia J, Zhang X, Jastrebova N, Spillmann D, Gottfridsson E, van Kuppevelt T, Zcharia E, Vlodavsky I, Lindahl U and Li J-P* (2007) Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate Nat Chem Biol 3, 773-778
 

 

Email:Jin-ping.Li@imbim.uu.se

 

Phone:+46 18 4714241

 

Office Location: B11:3, Biomedical Center, Uppsala, Sweden